Progress in HIV-1 vaccine development
نویسندگان
چکیده
منابع مشابه
Progress in HIV vaccine development.
Recent advances in HIV vaccine development include initiation of the first efficacy trials and substantial expansion of the preclinical pipeline. Several preclinical candidate vaccines have induced strong cellular immune responses and provided impressive protection against AIDS in non-human primate models; however, candidates that induce broadly neutralizing antibodies remain elusive.
متن کاملUpdate on progress in HIV vaccine development.
The 19th Conference on Retroviruses and Opportunistic Infections heralded the arrival of a new crop of potent, broadly neutralizing antibodies against HIV. This advance has given the entire vaccine field enormous hope that it will be possible one day to develop an antibody-based vaccine for HIV. However, substantial obstacles still exist in the induction of these antibodies by vaccination, give...
متن کاملHIV Vaccine Development: A Progress Report
• The development of a safe, effective preventive vaccine for human immunodeficiency virus (HIV) infection remains an area of vigorous research. Several highly innovative vaccine candidates are being developed, and more than 13 vaccine candidates have been tested in human phase I or II trials. All have produced antibody and several have produced modest neutralizing titers, but to date no reprod...
متن کاملHIV Vaccine development: Challenges and Progress
Currently 33.3 million people are estimated to be infected with HIV, with 2.6 million new infections occurring in 2009 alone (1). As we enter the fourth decade of the HIV epidemic, UNAIDS vision calls for zero discrimination, zero new HIV infections and zero AIDS related deaths through universal access to effective HIV prevention, treatment, care and support. Access to antiretroviral therapy (A...
متن کاملCurrent progress in the development of a prophylactic vaccine for HIV-1
Since its discovery and characterization in the early 1980s as a virus that attacks the immune system, there has been some success for the treatment of human immunodeficiency virus-1 (HIV-1) infection. However, due to the overwhelming public health impact of this virus, a vaccine is needed urgently. Despite the tireless efforts of scientist and clinicians, there is still no safe and effective v...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2013
ISSN: 1746-630X
DOI: 10.1097/coh.0b013e328361d178